![]() My FEV1 jumped from around 80% to over 90% (from my regular clinic visits). I could laugh without going into a coughing fit, and for the first time in my life I got a regular person cold that didn’t turn into an opportunistic infection or exacerbation. By the end of the month I was no longer coughing, I was fat, and I could sleep through the night. Within days, I experienced significant effects that I hadn’t experienced before, it was pretty obvious I wasn’t on placebo. Luckily a few years later I was able to get onto the phase III trial for Trikafta, and thankfully this time there was no doubt about its efficacy. Every time you see even the slightest positive change you want to attribute it to the drug and to be told you have to stop was difficult. Unfortunately after a few months of collecting data they discontinued the trial due to “futility”, this was difficult emotionally, as you want the drugs to work. I remember it was quite exciting to get onto a trial for a modulator as I had been paying attention to the research of ivacaftor and lumacaftor, and I wanted to experience the results that others were having. My journey with participating in clinical trials started a few years ago with a phase II study of a CFTR modulator that was not approved for my indication (one copy of deltaF508-CFTR). Paul’s hospital, and they have mostly been a positive experience. I have participated in a few clinical trials over the years, as well as multiple investigator studies at St. Please share your clinical trial experience: I am currently a community member of the recently formed CF Canada Accelerating Clinical Trials (CF CanACT) Network which aims to increase access and awareness for CF patients to participate in clinical trials across Canada. I have participated in many advocacy and fundraising activities for Cystic Fibrosis Canada, including GearUp4CF, the Rod Brind’amour & Nugent-Hopkins Golf Classic, and Shinerama. My research is focused on trying to better understand the mechanisms of action of the new CFTR modulators. I was diagnosed at 12 years of age at BC Children’s Hospital, I am heterozygous deltaF508, and I am currently working on my Ph.D. How many clinical trials have you participated in: 3ĭescribe yourself in one word: Advocate Please introduce yourself: Adult Cystic Fibrosis Advisory Committee.#CFCantWait | #laFKnattendpas Hashtag Wall.Research Study: Projecting the impact of delayed access to Trikafta.Accessing CF Medicines through Private Health Insurance.The Canadian Burkholderia Cepacia Complex Research and Referral Repository (CBCCRRR).Fertility and Family Planning Webinar Series.Transitioning from Pediatric to Adult Care.Collaborating with Your Clinic to Improve Your Healthcare.New International Guidelines on Mental Health in CF.Virtual Education Program for Patients and Caregivers.Hamilton graduated from Howard University in 2012 with a bachelor of arts in radio, TV and film. I’m grateful to Tunji and LaTrice for their incredible support and I’m excited to help break the next generation of superstar artists.” “The legacy of this brand is both rich and vast, and I am honored at the chance to add to it. “No entity in modern music has had a more profound impact on culture than Def Jam,” said Hamilton. “I’m thrilled to be reunited with Mike at this legendary label, and look forward to making more history together at Def Jam/4th & Broadway.” “Going back to our days at Atlantic, I’ve had a front row seat for Mike’s rapid growth as an executive and the passion, creativity and dynamism he brings to the job every day,” added LaTrice Burnette, executive vp Def Jam and president at 4th & Broadway. ![]() Hamilton launched his career in music at Atlantic Records, where he rose through the ranks to become senior manager of streaming and sales. At the label, he developed and oversaw strategies for artists including Cardi B, Lil Uzi Vert, Meek Mill, Janelle Monáe and Nipsey Hussle. Prior to his new role, Hamilton served for three years as senior director of commerce at Epic Records, where he devised strategies and led successful campaigns for an array of multi-platinum artists including DJ Khaled, BIA, Jennifer Hudson and Rick Ross. ![]()
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